Hematology

Biography

Biography: Lucia Stančiaková

Abstract

Aetiopathogenesis of venous thromboembolism and arterial thrombosis is associated with inherited and/or acquired risk factors. However, in some patients, despite the co-existence of several prothrombotic risk factors, the thrombotic episode does not develop. On the contrary, in some of them, thromboembolic event  may be detected without known provoking factor. Therefore, the authors analyzed risk factors and circumstances of the onset of thromboembolic events in subjects followed-up at the National Centre of Haemostasis and Thrombosis in Slovak Republic. In this study, the impact of acquired risk factors on the development of arterial and venous thrombosis, as well as their influence on pregnancy complications was confirmed. In selected group of patients, the impact of the acquired thrombophilia  on the development of thrombotic complications was evaluated. The results of laboratory tests, such as increased protein S deficiency, antithrombin deficiency, activity of coagulation factor VIII may be used in the targeted management of the risky patients.  This study complies with the Declaration of Helsinki and informed consent of the patient included in the study was obtained.

Acknowledgement: Authors thank the support of the projects of the Scientific Grant Agency Vega 1/0549/19 and the Agency for the Support of Research and Development APVV-16-0020.