Dr. Salma AlDallal has completed her PhD at the age of 32 from the University of Manchester, UK. He has pulished more than 14 articles in reputated journals and has a work experience in Haematology and Blood Bank Laboratory.
Sickle cell disease (SCD) is a group of disorders that affects hemoglobin, the red pigment in blood erythrocytes responsible for delivering oxygen throughout the body. This is the most commonly inherited blood disorder. One of the most widespread manifestations of SCD is painful vaso-occlusive crises and osteomyelitis. Dactylitis or hand-foot syndrome is the first clinical sign of SCD among children under the age of 6 years, particularly for those aged 1-2 years. Sickle cell dactylitis, an acute vaso-occlusive condition is associated with pain and edema on the dorsum of hands or feet or both simultaneously, along with elevated local temperature and erythema. This review will detail the problems associated with the bone and skeletal involvement in SCD with specific emphasis.