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Rosa Visone


Rosa Visone

G. D’Annunzio University, Italy

Biography

Rosa Visone has her expertise in studies related to microRNAs as diagnostic, prognostic and therapeutic tools in cancer. She developed this interest during her Postdoctoral position in Dr. Croce’s Laboratory. She identified microRNAs that can mark chronic lymphocytic leukemia (CLL) progression facilitating decision making for management of CLL patients. Her research also highlighted the cryptic promoter of miR-15a and miR-16-1, which seems to have a role in B-CLL cells from patients with more severe course of the leukemia.

Abstract

Abstract : MiR-181b in B cells of chronic lymphocytic leukemia is regulated by cellular interaction with CD4+ T cells and increases the CTL toxicity versus the leukemic clone