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Knox Van dyke

Knox Van dyke


West Virginia University


Knox Van Dyke has completed his PhD in Biochemistry in the Nobel Prize Department of Dr. Edward A Doisy at Saint Louis University in 1966. He began to study about malaria at West Virginia University Medical School and developed the first high throughput screening system for anti-malarial drugs identifying mefloquine and halofantrine which were commercially developed. He and Associate Professor Zuguang Ye recognized bisbenzylisoquinolines synergize with chloroquine causing resistance reversal to chloroquine as demonstrated in Aotus monkeys creating a malarial cure. He has edited and published 7 books for CRC Press, Boca Raton Florida and has written over 300 manuscripts.

Research Interest